OPEN CALL for 1 PhD Fellow position (36 months)

PERIPHERAL IMMUNITY IN PARKINSON’S DISEASE

OPEN CALL for 1 PhD Fellow position (36 months)

The Center for Research in Medical Pharmacology, University of Insubria (Varese, Italy) has an open PhD fellowship position to work on the role of peripheral immunity in Parkinson's disease with particular regard its relationship with neuroinflammation and neurodegeneration.

The ideal candidate for this PhD fellowship position (dottorato di ricerca) is expected to hold an MD or BSc degree or similar. During the PhD fellowship, s/he will learn and apply:
- flow cytometry techniques for the characterization of main innate and adaptive immune cell subsets in whole blood;
- cell separation and culture protocols, with regard to human granulocytes, monocytes and T lymphocytes purification and culture from buffy coats and whole blood;
- ex vivo/in vitro functional models of immune response;
- how to write scientific reports and manuscripts.
Knowledge of scientific english is an absolute requirement.

The position is open for 36 months. Salary will be 65.956,16 €/3 years (including taxes/social security and 6 months increase for travelling abroad).

The profile of the PhD program in Clinical and Experimental Medicine and Medical Humanities is available at:

- https://www.uninsubria.it/postlauream/medicina-clinica-e-sperimentale-e-medical-humanities-xxxv-ciclo

The official call detailing deadlines and procedures is available at:
- https://www.uninsubria.it/opportunita/ammissione-ai-dottorati-di-ricerca-xxxv-ciclo-aa-20192020 (italian)
- https://www.uninsubria.eu/opportunity/call-phd-xxxv (english)
Please refer to PhD program in Clinical and Experimental Medicine and Medical Humanities.
Deadline for application: 31 July 2019.

For more information please contact: farmacologia.medica@uninsubria.it.
E-mail submissions must include the subject “PhD position”.

References
Storelli E, Cassina N, Rasini E, Marino F, Cosentino M. Do Th17 Lymphocytes and IL-17 Contribute to Parkinson's Disease? A Systematic Review of Available Evidence. Front. Neurol., 24 January 2019 | https://doi.org/10.3389/fneur.2019.00013
Kustrimovic N, Comi C, Magistrelli L, Rasini E, Legnaro M, Bombelli R, Aleksic I, Blandini F, Minafra B, Riboldazzi G, Sturchio A, Mauri M, Bono G, Marino F, Cosentino M. Parkinson's disease patients have a complex phenotypic and functional Th1 bias: cross-sectional studies of CD4+ Th1/Th2/T17 and Treg in drug-naïve and drug-treated patients. J Neuroinflammation. 2018 Jul 12;15(1):205. doi: 10.1186/s12974-018-1248-8.
Cosentino M, Kustrimovic N, Marino F. β2-Adrenergic Agonists for Parkinson’s Disease: Repurposing Drugs at the Crossroad of the Brain and the Immune System. BrainImmune - Trends in Neuroendocrine Immunology (online), 2 december 2017.
Kustrimovic N, Rasini E, Legnaro M, Bombelli R, Aleksic I, Blandini F, Comi C, Mauri M, Minafra B, Riboldazzi G, Sanchez-Guajardo V, Marino F, Cosentino M. Dopaminergic Receptors on CD4+ T Naive andMemory Lymphocytes Correlate with Motor Impairment in Patients with Parkinson'sDisease. Sci Rep. 2016 Sep 22;6:33738.
Marino F, Cosentino M. Multiple sclerosis:Repurposing dopaminergic drugs for MS--the evidence mounts. Nat Rev Neurol. 2016 Apr;12(4):191-2.